4.8/5 based on 28,748 reviews
CelluVive PDRN Lip Care Duo for Day & Night
MediCure PDRN Lip Revival Duo pairs daytime jelly gloss with overnight sleeping mask — the hidden secret behind plump, hydrated lips and all-day confidence without constant reapplication.
Just one application daily transforms your lips — automatically adding moisture, volume, and smoothness while repairing them with every use.
- PDRN repairs damaged lips while boosting natural volume
- Dual formula hydrates twenty-four hours without stickiness
- Peptides add firmness, smoothness, and youthful definition
SELLING OUT FAST
Due to high demand, limited quantities available
93% SOLD
How Does It Work?
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The Science Behind MediCure PDRN Lip Revival Duo
Modern life constantly attacks your lips with harsh elements — and that may be why they appear cracked, thin, or constantly dry. Air conditioning, heating, sun exposure, and constant talking dehydrate delicate lip skin and destroy their ability to hold moisture and maintain plumpness. Your lips, just like your face, need:
✅ Deep Repair – to fix cracked, damaged tissue from the inside out
✅ Lasting Hydration – to lock in moisture for hours without reapplication
✅ Volume Support – to appear fuller and more youthful naturally
✅ Protection – to shield against environmental damage all day long
Without proper repair and hydration, lips lose their ability to stay smooth and plump, making you look tired, aged, or dehydrated even when you're not.
MediCure PDRN Lip Revival Duo delivers a two-step transformation with day gloss plus night mask, helping your lips:
Repair damaged tissue with Salmon DNA PDRN and collagen
Boost visible volume, smoothness, and natural pink tone instantly
Lock in moisture with hyaluronic acid, ceramides, and shea butter
Protect and firm with peptide complex and antioxidants
Build healthier, plumper-looking lips with each application
With just two simple steps, MediCure PDRN Lip Revival Duo turns cracked, thin lips into soft, voluminous, kissably smooth lips — giving you stronger, more beautiful lips from the cellular level up.
What Can MediCure PDRN Lip Revival Duo Help With?
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💧 Constant Dry, Cracked Lips
Environmental stress and dehydration cause painful cracking and peeling that never seems to heal. MediCure PDRN Lip Revival Duo delivers deep cellular repair with Salmon DNA PDRN that actually rebuilds damaged lip tissue, giving you smooth, crack-free lips that stay soft all day.
💄 Lipstick That Won't Apply Smoothly
When your lips are dry and flaky, lipstick clings to dead skin and looks patchy within hours. MediCure PDRN creates a perfectly smooth canvas with its peptide jelly gloss base, making lipstick glide on flawlessly and last longer without feathering or fading.
👄 Thin, Deflated-Looking Lips
Aging, dehydration, and collagen loss make lips appear thinner and less defined over time. MediCure PDRN's collagen-boosting formula clinically increased lip volume by 5.68% after just one use, giving you naturally fuller, more youthful-looking lips without injections.
😣 Embarrassing Peeling and Flakiness
Dead skin buildup makes lips look unhealthy and draws negative attention in close conversations. MediCure PDRN reduced lip flakiness by 77.6% in clinical testing, eliminating embarrassing peeling and giving you smooth, photo-ready lips.
🌡️ Lips That Can't Handle Weather Changes
Winter wind, summer sun, and indoor heating constantly strip moisture from delicate lip skin. MediCure PDRN's dual-action system protects lips around the clock with ceramides and shea butter that create a moisture barrier against harsh conditions.
😴 Waking Up With Chapped Lips
Overnight mouth breathing and dry air leave lips cracked and painful by morning. MediCure PDRN Lip Sleeping Mask delivers intensive repair while you sleep, so you wake up with soft, hydrated, comfortable lips every single morning.
💋 Lips That Make You Look Older
Fine lines, dullness, and loss of definition age your entire face. MediCure PDRN's peptide complex firms and smooths lip contours while adding a subtle pink glow, taking years off your appearance instantly.
😔 Constant Reapplication That Never Works
Regular lip balms provide temporary relief but lips feel dry again within an hour. MediCure PDRN's 24-hour moisture lock technology keeps lips hydrated all day and all night, freeing you from the constant reapplication cycle.
When Will I See Results?
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⏳ During Your First Application
Many users notice instant gloss, hydration, and smoothness with the first swipe. The jelly gloss formula floods lips with moisture while the silver pearl shimmer creates an immediate plumping effect that makes lips look fuller and more defined. Some users report lips feeling softer and looking more voluminous right after their first application.
📅 After 2–3 Days of Consistent Use
With daily day and night application, lips begin to repair from the cellular level thanks to PDRN and collagen working deep in the tissue. Many users notice significantly less peeling, improved moisture retention that lasts for hours, and a natural pink tone returning to pale lips. This is often when the embarrassing flakiness completely disappears.
🔁 With Ongoing Daily Use
The real transformation comes with consistency: making MediCure PDRN Lip Revival Duo part of your daily routine creates permanent improvements in lip texture, volume, and resilience. Over time, users commonly report lips that stay hydrated without constant reapplication, visible plumping that makes them look years younger, and confidence in close-up photos and conversations without worrying about cracked, aged-looking lips.
How Long Until I Get It?
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All MediCure PDRN Lip Revival Duo sets are shipped directly from our US distribution centers with care and premium protective packaging. Orders are typically processed and dispatched within 1–2 business days. Most customers receive their order within 3–5 business days, depending on their location. A tracking number will be sent to you as soon as your package is on its way.
Who Can Use It?
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MediCure PDRN Lip Revival Duo is designed for anyone who wants soft, plump, youthful lips without constant maintenance or expensive injections. It's especially perfect for:
Busy professionals who need lips that stay perfect from morning meetings to evening events
Makeup lovers looking for a smooth, hydrated base that makes lipstick apply flawlessly
Anyone with chronically dry lips who's tired of products that only work temporarily
Women concerned about aging lips who want natural volume and firmness without needles
People who wake up with cracked lips and need overnight repair that actually works
Social butterflies who want confidence in close conversations without embarrassing peeling
Anyone tired of sticky, waxy lip products that feel heavy and uncomfortable
This lip-transforming duo works safely for daily use, is dermatologist tested, and gentle enough for even the most sensitive lips. If you want lips that stay soft, smooth, and naturally plump all day and all night without constant reapplication... this was made for you.
See it in action
Over 4.4M Views On Instagram
Ruby T.
My lips have never looked this good. The jelly gloss gives me instant shine and volume during the day, and the sleeping mask actually repairs the cracks overnight. I wake up with soft, kissable lips for the first time in years.
Elevating Your Lip Care Game
Discover the outstanding features that make our product stand out from the competition.
Elevating Your Lip Care Game
Discover the outstanding features that make our product stand out from the competition.
Salmon DNA PDRN Power
Clinically proven to repair damaged lip tissue at the cellular level for lasting results.
Dual Day & Night System
Jelly gloss hydrates during the day while sleeping mask rebuilds overnight for 24-hour transformation.
Instant Volume Boost
Increases visible lip volume by 5.68% after just one application without injections.
Medical-Grade Hydration
Hyaluronic acid, ceramides, and peptides lock moisture in for hours without stickiness.
Plump, Perfect Lips In Just Two Simple Steps
We Don't Stop — We Push Lip Care Limits Further
Cellular Repair
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PDRN works at the DNA level to rebuild damaged lip tissue permanently.
Zero Stickiness
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Lightweight jelly texture absorbs instantly without the heavy, waxy feeling.
Natural Plumping
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Collagen and peptides boost lip volume without needles or harsh chemicals.
Moisture Lock
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Advanced ceramide barrier prevents moisture loss for true 24-hour hydration.
Perfect Canvas
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Creates smooth, flake-free lips that make lipstick apply like a professional artist.
Youth Restoration
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Firms lip contours and reduces fine lines for a visibly younger appearance.
Real Feedback From MediCure PDRN Lip Revival Duo Customers
Our results prove why we're the industry leader.
Real Feedback From MediCure PDRN Lip Revival Duo Customers
Our results prove why we're the industry leader.
0K+
Transformed Lips
Thousands trust MediCure PDRN for softer, fuller, permanently hydrated lips.
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Satisfaction Rate
Fewer than 6% of customers reported being unsatisfied with results.
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Returning Clients
Nearly 4 out of 5 reorder to maintain their plump, youthful lip transformation.
Results based on a voluntary, self-reported customer survey conducted on MediCure PDRN Lip Revival Duo users in 2024. Individual results may vary.
The MediCure PDRN Difference
See The Dramatic Lip Transformations MediCure PDRN Delivers — Real Results From Real Customers.
After
Before
You Can Expect
- Instant Volume
- Cellular Repair
- Zero Stickiness
- Perfect Canvas
- 24Hr Moisture
Why ChooseMediCure PDRN Lip Revival Duo?
Here's Why We're The Lip Care Leader
Why ChooseMediCure PDRN Lip Revival Duo?
Here's Why We're The Lip Care Leader
With medical-grade Salmon DNA PDRN, dual day and night formulas, and clinically proven volume increase, MediCure PDRN Lip Revival Duo sets the standard for modern lip repair and transformation.
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PDRN LIP REVIVAL DUO
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Medical-grade cellular repair
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24-hour transformation protocol
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+5.68% visible plumping
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Absorbs instantly, feels invisible
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Needs reapplication every hour
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Join Over 28,000+ Happy Customers.
Kelly,
31
Verified Buyer
I've tried every lip product on the market and nothing worked until MediCure PDRN. The jelly gloss is like nothing I've ever used — it actually makes my lips look fuller instantly, and the sleeping mask completely healed my cracked lips in three days. My husband even noticed and asked what I was doing differently!
CelluVive PDRN Lip Care Duo for Day & Night
$39.95 $79.90
Purchased on March 14th, 2025
Jessica,
36
Verified Buyer
This duo changed my life. I used to be so embarrassed about my peeling lips in meetings and photos, but now they're smooth, soft, and naturally pink all day long. The best part? My lipstick finally stays on without looking patchy. Worth every single penny.
CelluVive PDRN Lip Care Duo for Day & Night
$39.95 $79.90
Purchased on March 14th, 2025
Ann,
28
Verified Buyer
I'm obsessed with the sleeping mask. I wake up with lips that look like I just applied balm, but it's been working all night. My lips are visibly plumper and the fine lines around them are disappearing. This is the only lip product I'll ever need.
CelluVive PDRN Lip Care Duo for Day & Night
$39.95 $79.90
Purchased on March 14th, 2025
Frequently Asked Questions
Find answers to common questions about our products, shipping, returns, and more.
What is the MediCure PDRN Lip Revival Duo?
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MediCure PDRN Lip Revival Duo is a 2-step lip transformation system combining a daytime peptide jelly gloss with an overnight lip sleeping mask. Together, they create softer, fuller, permanently hydrated lips using medical-grade Salmon DNA PDRN that repairs lip tissue at the cellular level.
How is this different from regular lip balm?
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Unlike temporary lip balms that just coat the surface, MediCure PDRN uses Salmon DNA (PDRN) to actually repair damaged lip cells and rebuild tissue from the inside out. This means results that last instead of wearing off in an hour. Plus, our dual system works 24 hours — daytime gloss for instant volume and nighttime mask for deep repair while you sleep.
What is PDRN and why does it work?
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PDRN (Polydeoxyribonucleotide) is extracted from salmon DNA and is clinically proven to regenerate damaged tissue at the cellular level. It's used in medical skin treatments and anti-aging procedures because it actually rebuilds collagen and repairs cells instead of just temporarily moisturizing. This is why MediCure PDRN delivers permanent improvement, not just temporary relief.
Will this make my lips look plumper?
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Yes. Clinical testing showed a 5.68% increase in visible lip volume after just one application. The jelly gloss creates instant plumping with hyaluronic acid and peptides, while the sleeping mask builds natural volume over time by boosting collagen production with PDRN. You get both immediate and long-term plumping without needles or irritation.
Is it sticky or heavy like other glosses?
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No. The jelly texture is completely different from traditional sticky glosses. It absorbs quickly and feels lightweight and comfortable, not heavy or waxy. Many customers say they forget they're wearing it because it feels so natural.
How do I use both products?
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Morning: Apply the Peptide Jelly Gloss to clean lips for instant hydration, shine, and volume. Reapply throughout the day as needed or wear under lipstick for a smooth base. Night: Apply a generous layer of the Lip Sleeping Mask before bed and let it work while you sleep to repair and rebuild lip tissue overnight.
Can I wear it under lipstick?
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Absolutely. The jelly gloss creates the perfect smooth, hydrated base that makes lipstick glide on flawlessly and last longer. Many customers apply the gloss first, let it absorb for 30 seconds, then apply their favorite lipstick on top for all-day color that doesn't crack or fade.
Is it safe for sensitive lips?
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Yes. MediCure PDRN Lip Revival Duo is dermatologist tested, hypoallergenic, and formulated without harsh irritants. The gentle, low-irritation formula is specifically designed for even the most sensitive lips and can be used daily without any burning or tingling.
